At first, switch your browser into full-screen mode (Press F11 key, ^⌘F combination or use the menu) to verify every pixel of your display.
Wipe dust and dirt off the screen using a serviette or a piece of cloth. Use different color modes (tap, click or press a space bar) to find defective pixels.
Note: F11 or ^⌘F toggles Full-Screen mode On and Off. Spacebar or Enter key switches the color mode.